Glucose signalling positively regulates aliphatic glucosinolate biosynthesis

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Glucose signalling positively regulates aliphatic glucosinolate biosynthesis

The effects of glucose on aliphatic glucosinolate biosynthesis in Arabidopsis thaliana were investigated in this study by using mutants related to aliphatic glucosinolate biosynthesis and regulation, as well as glucose signalling. The results showed that glucose significantly increased the contents of individual and total aliphatic glucosinolates. Expression of MYB28 and MYB29, two key transcri...

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Glucosinolates (GSLs) are amino acid-derived secondary metabolites with diverse biological activities dependent on chemical modifications of the side chain. We previously identified the flavin-monooxygenase FMO(GS-OX1) as an enzyme in the biosynthesis of aliphatic GSLs in Arabidopsis (Arabidopsis thaliana) that catalyzes the S-oxygenation of methylthioalkyl to methylsulfinylalkyl GSLs. Here, we...

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The distinctive flavors and anticarcinogenic properties of cruciferous vegetables are largely due to the presence of glucosinolates. These sulfur-rich metabolites are derived from one of several amino acids via three stages: (1) elongation of the amino acid side chain; (2) formation of the core glucosinolate skeleton; and (3) secondary modification of the side chain (reviewed in Grubb and Abel,...

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Glucose enhances indolic glucosinolate biosynthesis without reducing primary sulfur assimilation

The effect of glucose as a signaling molecule on induction of aliphatic glucosinolate biosynthesis was reported in our former study. Here, we further investigated the regulatory mechanism of indolic glucosinolate biosynthesis by glucose in Arabidopsis. Glucose exerted a positive influence on indolic glucosinolate biosynthesis, which was demonstrated by induced accumulation of indolic glucosinol...

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Novel insights into the function of Arabidopsis R2R3-MYB transcription factors regulating aliphatic glucosinolate biosynthesis.

Arabidopsis transcription factors, MYB28, MYB29 and MYB76, positively regulate aliphatic glucosinolate (AGSL) biosynthesis. Mutual transcriptional regulation among these MYB genes makes it difficult to elucidate their individual function simply by analyzing knock-out mutants or ectopically overexpressing lines of these genes. In this study, we constructed transgenic lines expressing each MYB ge...

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ژورنال

عنوان ژورنال: Journal of Experimental Botany

سال: 2013

ISSN: 1460-2431,0022-0957

DOI: 10.1093/jxb/ers399